第四十一期水木清华生命科学讲座系列
朱冰博士1971年出生于中国南京，1992年毕业于浙江大学，1999年获中国科学院上海植物生理研究所分子遗传博士。现为中国科学院生物物理所研究员。
自2006年以来，朱冰博士领导的实验室主要从事表观遗传学研究，阐明了复制过程中组蛋白的分配模式和组蛋白修饰的重建过程，否定了组蛋白修饰承载的表观遗传信息以组蛋白密码方式精确继承的模型，提出了组蛋白修饰的反馈维持模型。近期，朱冰实验室还对DNA甲基化的动态调控开展了新的探索。朱冰博士2012年入选美国霍华德-休斯医学院国际青年科学家，2014获谈家桢生命科学创新奖。
Topic : Establishment & Maintenance of Epigenetic Information
Speaker:
Bing Zhu, Ph.D.
Investigator
Institute of Biophysics, Chinese Academy of Sciences
Abstract:
DNA is unarguably the carrier of genetic information. However, DNA sequence alone cannot explain how hundreds of cell types in a complex multi-cellular organism, such as a human individual can possess hundreds of distinct transcription programs, while sharing the same genetic information. This is believed to be achieved by fine-tuning our genetic information with a so-called “epigenetic” system. To fulfill the two basic tasks challenging the multi-cellular organisms, epigenetic system must simultaneously offer dual characteristics, “Plasticity & Inheritability”. Plasticity allows the transformation of one genome into hundreds of epigenomes and transcriptomes, whereas inheritability permits the maintenance of every single epigenome and its corresponding transcriptome.
I will highlight some of our recent progresses discussing the dynamics and underlying mechanisms of the establishment and maintenance of epigenetic information.
时间：2016年5月5日 15:00-16:00
地点：医学科学楼B323
