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清华大学生物论坛 讲座
发布时间:2012-12-05关键字:清华大学生物论坛

Tobias Walther, Ph.D.

Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA
 
ACADEMIC APPOINTMENTS
2010-present        Associate Professor of Cell Biology, Yale School of Medicine, New Haven, CT
2010-2012           Visiting Faculty, Max Planck Institute of Biochemistry, Martinsried, Germany
2006-2010           Group Leader, Max Planck Institute of Biochemistry, Martinsried, Germany
 
POSTDOCTORAL TRAINING
2002-2006           UCSF, San Francisco, Department of Biochemistry and Biophysics in the laboratory of Dr. Peter Walter: “Homeostasis of the plasma membrane”.
 
EDUCATION
2002           Dr. rer. nat (Ph.D) in biology, summa cum laude from EMBL/Ludwig-Maximilians University, Munich
2000           Paterson research Institute, Manchester
1998           Diploma in Biology (Dipl. Biol.) from Ludwig-Maximilans University, Munich, with distinction (1,0).
1997           Southern Methodist University, Dallas
 
Topic: The Many Phases of Fat: Cell Biology of Lipid Droplets
 
Abstract
Most cells store excess metabolic energy in the form of fat that is stored in cytosolic Lipid Droplets (LDs). LD function at critical points of cellular physiology: Not surprisingly therefore, LDs are involved in many common diseases, such as metabolic syndrome, fatty liver disease, atherosclerosis and obesity. Despite their almost universal presence and links to common human pathologies, many basic questions about LDs are unclear. LDs thus provide both great challenges and opportunities for cell biology. Within this field, we specifically address how lipid droplets are built, how they grow, how they contribute to the organization of biochemical pathways and how lipids get stored and utilized there. Building on cell biological discoveries, we connect mechanistic studies of LDs with their important functions in disease.
 
Venue: Room143, New Biology Building, THU
Time: Dec. 18 (Tuesday), 2012; 16:30
Host: Prof. Peng Li

 




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