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6月28日清华大学生物论坛 - Xiaole Shirley Liu
发布时间:2016-06-24关键字:

Computational Biology in Translational Cancer Research




 

Xiaole Shirley Liu, PhD

Harvard School of Public Health


 

Biography:

Dr. Xiaole Shirley Liu is an expert in computational biology, genomics and epigenetics of gene regulation, and cancer biology. She is member of the mod/ENCODE consortia (NHGRI) and Information Technology for Cancer Research initiative (NCI), an associate member at the Broad Institute, and the co-director (with Myles Brown) of the Center for Functional Cancer Epigenetics at the Dana-Farber Cancer Institute. Her group focuses on algorithm development and integrative modeling for translational cancer research.

 

Abstract:

Computational biology is playing important roles in precision cancer therapy. I will discuss our efforts using computational biology to mine high throughput sequencing data in order to aid translational cancer research. Specifically I will discuss three areas of our current foci: using public ChIP-seq data to understand cancer gene regulation, using CRISPR screen data to identify tumor vulnerabilities and targeted combination therapy, and using RNA-seq data to model tumor infiltrating immune cells and T-cell repertoires. 


Time:  June 28, 2016 16:00-17:00

Venue:  Room 143, New Biology Building

Host:    Dr. Zhi Lu

举办单位:生命科学联合中心

 

 




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