Metabolism and Trafficking of Cholesterol in Mammalian Cells
Baoliang Song Ph.D.
Professor and Dean,
College of Life Sciences,
Wuhan University, Wuhan,
Biography：
Prof. Song received his B.S. degree from Nanjing University in 1997. After he was awarded the Ph.D. diploma from Chinese Academy of Sciences in 2002, he joined the UT Southwestern Medical Center as a Postdoctoral Fellow. In 2005, he moved to Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences at Chinese Academy of Sciences as a Principle Investigator, and then he worked as a professor and was promoted to Dean of College of Life Sciences, Wuhan University in 2014. He was awarded by the national natural science fund for distinguished young scholars and the major national scientific research project chief scientist in 2009. In 2013, he received the Arthur Kornberg Memorial Award and was selected for New Century Talents Project. He was awarded the Provo McGonagall Innovation by the Chinese Society for Cell Biology. Besides, Prof. Song also worked as the Associate Editor for J. of Molecular Cell Biology and an Editorial Board Member for J. Biol. Chem..
Abstract：
Prof. Song’s lab works on cholesterol homeostasis that is closely related to cardiovascular disease. His group has dissected the molecular pathway of intestinal cholesterol absorption and identified most of the protein in this process. He has uncovered the mechanism of sterol-regulated degradation of HMG-CoA reductase, which is a major feed-back regulation of de novo cholesterol biosynthesis. His group also identified betulin, a small molecule, which can decrease both cholesterol and fatty acid levels by inhibiting SREBP pathway. He has authored or co-authored over 40 publications in Cell, Nat. Med., PNAS, Nat. Commun., etc.
Time: Sept. 13th, 2016, 16:00-17:00
Venue: 清华大学医学科学楼B323
Host: Prof. Yu Rao
举办单位：生命科学联合中心
