刘 磊

 

研究领域:

1. 蛋白质的化学合成与生物医学应用

2. 生物活性小分子的催化合成及应用

 

近期主要论文：

1、 Fang, G.-M.; Li, Y.-M.; Shen, F.; Huang, Y.-C.; Li, J.-B.; Lin, Y.; Cui, H.-K.; Liu, L.* Protein chemical synthesis by ligation of peptide hydrazides. Angew. Chem. Int. Ed. 2011, 50, 7645-7649.

2、 Zheng, J.-S.; Chang, H.-N.; Wang, F.-L.; Liu, L.* Fmoc synthesis of peptide thioesters without post-chain-assembly manipulation. J. Am. Chem. Soc. 2011, 133, 11080-11083.

3、 Xiao, B.; Gong, T.-J.; Liu, Z.-J.; Liu, J.-H.; Luo, D.-F.; Xu, J.; Liu, L.* Synthesis of dibenzofurans via palladium-catalyzed phenol-directed C-H activation/C-O cyclization. J. Am. Chem. Soc. 2011, 133, 9250-9253.

4、 Yang, C.-T.; Zhang, Z.-Q.; Liu, Y.-C.; Liu, L.* Copper-catalyzed cross-coupling reaction of organoboron compounds with primary alkyl halides and pseudohalides. Angew. Chem. Int. Ed. 2011, 50, 3904-3907.

5、 Shang, R.; Ji, D.-S.; Chu, L.; Fu, Y.; Liu, L.* Synthesis of a-aryl nitriles through palladium-catalyzed decarboxylative coupling of cyanoacetate salts with aryl halides and triflates. Angew. Chem. Int. Ed. 2011, 50, 4470-4474.

6、 Xiao, B.; Gong, T.-J.; Xu, J.; Liu, Z.-J.; Liu, L.* Palladium-catalyzed intermolecular directed C-H amidation of aromatic ketones. J. Am. Chem. Soc. 2011, 133, 1466-1474.