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电子邮件: yanshi@biomed.tsinghua.edu.cn
电话:+86-10-62797488
  
科研方向
免疫学,树突状细胞生理,疫苗,自体免疫调控,原子力显微镜基础上的单细胞激活研究
 
代表性科研论文
1. Shi Y. To forge a solid immune recognition. Protein Cell 3(8):564-70, 2012 Aug.
2. Ghaemi Oskouie, F., A. Shameli, A. Yang, M. D. Desrosiers, A. D. Mucsi, M. R. Blackburn, Y. Yang, P. Santamaria, and Y. Shi. 2011. High levels of adenosine deaminase on dendritic cells promote autoreactive T cell activation and diabetes in nonobese diabetic mice. J Immunol 186:6798-806.
3. Flach, T. L., G. Ng, A. Hari, M. D. Desrosiers, P. Zhang, S. M. Ward, M. E. Seamone, A. Vilaysane, A. D. Mucsi, Y. Fong, E. Prenner, C. C. Ling, J. Tschopp, D. A. Muruve, M. W. Amrein, and Y. Shi. 2011. Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med 17: 479-87.
4. Kanevets, U., K. Sharma, K. Dresser, and Y. Shi. 2009. A role of IgM antibodies in monosodium urate crystal formation and associated adjuvanticity. J Immunol 182: 1912 -1918.
5. Ng, G., K. Sharma, S. M. Ward, M. D. Desrosiers, L. A. Stephens, W. M. Schoel, T. Li, C. A. Lowell, C. C. Ling, M. W. Amrein, and Y. Shi. 2008. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity 29: 807-18.
6. Desrosiers, M. D., K. M. Cembrola, M. J. Fakir, L. A. Stephens, F. M. Jama, A. Shameli, W. Z. Mehal, P. Santamaria, and Y. Shi. 2007. Adenosine deamination sustains dendritic cell activation in inflammation. J Immunol 179: 1884-92.
7. Shi, Y., J. E. Evans, and K. L. Rock. 2003. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425: 516-21.
 
 
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