陆林 

 

电子邮件: linlu(at)bjmu(dot)edu(dot)cn；

电话: 86-10-82802459；

实验室主页: http://jichu.bjmu.edu.cn/teacher/ShowArticle.asp?ArticleID=48

 

研究方向:
抑郁症和药物依赖的神经生物学和临床治疗学研究。采用动物研究及人体研究相结合的模式，综合运用分子生物学、药理学、电生理、分子遗传学、心理学及神经影像学手段，研究 （1）抑郁症和药物依赖的脑内突触可塑性改变；（2）病理性记忆动态变化的分子生物学机制；（3）抑郁症和药物依赖的心理、认知的变化规律及其干预手段。

 

代表性科研论文:

 

1. Xue YX, Luo YX, Wu P, Shi HS, Xue LF, Chen C, Zhu WL, Ding ZB, Bao YP, Shi J, Epstein DH, Shaham Y, Lu L. A memory retrieval-extinction procedure to prevent drug craving and relapse. Science. 2012 Apr 13; 336(6078):241-5.

2. Zhang XL, Shi J, Zhao LY, Sun LL, Wang J, Wang GB, Epstein DH, Lu L. .Effects of Stress on Decision-Making Deficits in Formerly Heroin-Dependent Patients After Different Durations of Abstinence. Am J Psychiatry. 2011 Jun; 168(6):610-6.

3. Wang X, Luo YX, He YY, Li FQ, Shi HS, Xue LF, Xue YX, Lu L. Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats. J Neurosci. 2010 Sep 22;30(38):12632-41.

4. Li SX, Shi J, Epstein DH, Wang X, Zhang XL, Bao YP, Zhang D, Zhang XY, Kosten TR, Lu L. Circadian Alteration in Neurobiology During 30 Days of Abstinence in Heroin Users. Biol Psychiatry. 2009; 65(10):905-12.

5. Lu L, Hope BT, Dempsey J, Liu SY, Bossert JM, Shaham Y. Central amygdala ERK signaling pathway is critical to incubation of cocaine craving. Nat Neurosci. 2005, 8:212-219.