Yule Liu
Research Area
1) Signal transduction and regulation of plant immunity
2) Molecular basis of plant viral pathogenesis
3) Plant autophagy
Selected Publications
1. Wang J, Chen T, Zhang Z, Song M, Shen T, Wang X, Zheng X, Wang Y, Song K, Ge X, Xu K, Qi T, Li F, Hong Y, Liu Y*. Remodelling autoactive NLRs for broad-spectrum immunity in plants, Nature 645(8081):737-745, 2025
2. Gong Q, Wang Y, He L, Huang F, Zhang D, Wang Y, Wei X, Han M, Deng H, Luo L, Cui F, Hong Y, Liu Y*. Molecular basis of methyl-salicylate-mediated plant airborne defence, Nature 622(7981):139-148, 2023
3. Yang M, Ismayil A, Jiang Z, Wang Y, Zheng X, Hong Y, Li D*, Liu Y*. A viral protein disrupts vacuolar acidification to facilitate virus infection in plants, EMBO Journal 41(2): e108713, 2022
4. Wang Y, Gong Q, Wu Y, Huang F, Ismayil A, Zhang D, Li H, Gu H, Ludman M, Fátyol, Qi Y, Yoshioka K, Hanley-Bowdoin L, Hong Y, Liu Y*. A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants, Cell Host & Microbe 29, 1393–1406, 2021
5. Li H, Zhang D, Xie K, Wang Y, Liao Q, Hong H, Liu Y*. Efficient and high-throughput pseudorecombinant-chimeric Cucumber mosaic virus-based VIGS in maize. Plant Physiology 187(4):2865-2876, 2021
6. Wang J, Chen T, Han M, Qian L, Li J, Wu M, Han T, Cao J, Nagalakshmi U, Rathjen JP, Hong Y, Liu Y*. Plant NLR immune receptor Tm-22 activation requires NB-ARC domain-mediated self-association of CC domain. PLoS Pathogens 16(4):e1008475, 2020
7. Ismayil A, Yang M, Haxima Y, Wang Y, Li J, Han L, Wang Y, Zheng X, Wei X, Nagalakshmi U, Hong Y, Hanley-Bowdoin L, Liu Y*. Cotton leaf curl Multan virus βC1 protein induces autophagy by disrupting the interaction of autophagy related protein 3 with Glyceraldehyde-3 Phosphate Dehydrogenases. Plant Cell 32(4):1124-1135, 2020
8. Ismayil A, Haxim Y, Wang Y, Li H, Qian L, Han T, Chen T, Jia Q, Yihao Liu A, Zhu S, Deng H, Gorovits R, Hong Y, Hanley-Bowdoin L, Liu Y*. Cotton Leaf Curl Multan virus C4 protein suppresses both transcriptional and post-transcriptional gene silencing by interacting with SAM synthetase. PLoS Pathogens 14(8): e1007282, 2018
9. Haxim Y, Ismayil A, Jia Q, Wang Y, Zheng X, Chen T, Qian L, Liu N, Wang Y, Han S, Cheng J, Qi Y, Hong Y, Liu Y*, Autophagy functions as an antiviral mechanism against geminiviruses in plants. eLife 6, e23897., 2017
10. Xu G, Wang S, Han S, Xie K, Wang Y, Li J, Liu Y*, Plant Bax Inhibitor-1 interacts with ATG6 to regulate autophagy and programmed cell death. Autophagy 13(7):1161-1175, 2017
11. Jia Q, Liu N, Xie K, Dai Y, Han S, Zhao X, Qian L, Wang Y, Zhao J, Gorovits R, Xie D, Hong Y and Liu Y*, CLCuMuB βC1 Subverts Ubiquitination by Interacting with NbSKP1s to Enhance Geminivirus Infection in Nicotiana benthamiana, PLoS Pathogens 12(6): e1005668, 2016
12. Han S，Wang Y, Zheng X, Jia Q, Zhao J, Bai F，Hong Y and Liu Y*, Cytoplastic glyceraldehyde-3-phosphate dehydrogenases interact with ATG3 to negatively regulate autophagy and immunity in Nicotiana benthamiana, Plant Cell 27(4):1316-31, 2015
13. Du Y, Zhao J, Chen T, Liu Q, Zhang H, Wang Y, Hong Y, Xiao F, Zhang L, Shen Q and Liu Y*, Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity, PLoS Pathogens 9(10): e1003659, 2013
14. Wang Y, Yu B, Zhao J, Guo J, Li Y, Han S, Huang L, Du Y, Hong Y, Tang D, and Liu Y*，Autophagy Contributes to the Leaf Starch Degradation, Plant Cell 25(4): 1383-1399, 2013
15. Liu Y, Schiff M, Czymmek K, Talloczy Z., Levine B and Dinesh-kumar SP. Autophagy regulates programmed cell death during the plant innate immune response, Cell 121(4), 567-577, 2005
