Center PI

PAN JUNMIN

Emailpanjunmin@tsinghua.edu.cn

Research Area: Cytoskeleton and Signaling, Cilia Biology, Synthetic Biology of Microalgae

Selected publications

1.Wang Z., He R., Liu Q., Snell W. J.*, Cao, M.*, Pan, J.* 2025. A lipid flippase shapes the ciliary membrane and is essential for ciliogenesis. Curr Biol. 35:1-9. https://doi.org/10.1016/j.cin.2025.10.014

2.Zhang Y., Yang X., Pan J.*. 2025. Chlamydomonas protein kinase MAK phosphorylates FAP256/CEP104 and regulates axonemal microtubule assembly. PNAS. 22:e2503094122

3.Xu J*, Zhang Y., Pan, J.* 2025. Primary Cilia- Mediated Hedgehog Signaling Regulates Cell Fate During ER Stress Induced Life or Death Decisions. FASEB J. 39:e70982.

4.Li X., Zhang, Y., Wen X., Pan J.* 2024. Utilizing codon degeneracy in the design of donor DNA for CRISPR/Cas9-mediated gene editing to streamline the screening process for single amino acid mutations. Plant J. 119(4):2133-2143.

5.Junhao Huang, Hui Tao, Jikun Chen, Yang Shen, Jianlin Lei, Junmin Pan*, Chuangye Yan* and Nieng Yan*. 2024. Structure-guided discovery of protein and glycan components in native mastigonemes. Cell. 187:1733-1744.

6.Pan J. 2023. Ciliary disassembly. In The Chlamydomonas Sourcebook. Volume 3 – Cell Motility and Behavior (ed. S. Dutcher), pp. 357-372Oxford, UK: Elsevier, Inc.

7.Wang L, Li X, Liu G, Pan J*. 2022. FBB18 participates in preassembly of almost all axonemal dyneins independent of R2TP complex. PLos Genet. 18(8):e1010374.

8.Zhu X, Wang J, Li S, Lechtreck K, Pan J*. 2021. IFT54 directly interacts with kinesin-II and IFT dynein to regulate anterograde intraflagellar transport. EMBO J 40: e105781.

9.Li S, Wan KY, Chen W, Tao H, Liang X*, Pan J*. 2020. Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas. eLife 9:e58868.

10.Liang Y, Zhu X, Wu Q, Pan J*. 2018. Ciliary Length Sensing Regulates IFT Entry via Changes in FLA8/KIF3B Phosphorylation to Control Ciliary Assembly. Curr Biol. 28(15), 2429-2435.

11.Zhu B, Zhu X, Wang L, Liang Y, Feng Q, Pan J*. 2017.Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis. PLoS Genet. 13(2):e1006627.

12.Hu J, Liang Y, He W, Pan J *. 2015. Cilia disassembly with two distinct phases of regulation. Cell Reports 10, 1803-1810.

13.Liang Y, Pang Y, Wu Q, Hu Z, Han X, Xu Y, Deng H, Pan J*. 2014. FLA8/KIF3B phosphorylation regulates kinesin-II interaction with IFT-B to control IFT entry and turnaround. Dev Cell. 30, 585-597.

14.Cao M, Meng D, Wang L, Bei S, Snell WJ*, Pan J*. 2013. Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length. PNAS, 110, 12337-42.

Previous:Qi OUYANG
Next:Min Peng