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Ruiping XIAO

Ruiping XIAO


Email: xiaor(at)pku(dot)edu(dot)cn;

Telephone: +86-10-62757243;

Lab Homepage: http://www.imm.pku.edu.cn/news.php?id=29


Research Area:

The main scientific focus of Dr. Rui-Ping Xiao has been on G-protein coupled receptor (GPCR) signaling in the cardiovascular system. The scope of her scientific work covers two intertwined programs: (I) b-adrenergic receptor (bAR) subtype signaling in cardiovascular system: from bench to the bedside; (II) Identification and characterization of metabolic disease and cardiovascular disease-related genes and pathways. These studies integrate information gleaned from interdisciplinary approaches at multiple levels (molecule, pathways, transcriptome, proteome, cell, organ, and whole animal). Since April 2010, she has left NIH and started her career in Institute of Molecular Medicine, Peking University, Beijing, China.


Selected Publications:

1. Cao CM, Zhang Y, Weislede N, Ferrante C, Wang XH, Lv F, Zhang Y, Song RS, Hwang M, Jin L, Guo J, Peng W, Li G, Nishi M, Takeshima H, Ma J, Xiao RP*, MG53 constitutes a primary determinant of cardiac ischemic preconditioning. CIRCULATION, 121: 2565-74, 2010.

2. Chen KH, Guo XM, Ma DL, Guo YH, Li Q, Li P, Qiu X, Xiao RP*, Tang J, Dysregulation of A Novel Hyperplasia Suppressor Gene Triggers Vascular Proliferative Disorders. NATURE CELL BIOLOGY, 6:872-883, 2004.

3. Zhu WZ, Zheng M, Lefkowitz RJ, Koch WJ, Kobilka B, Xiao RP*, Dual modulation of cardiac cell survival and cell death by 2-adrenergic signaling in adult mouse heart cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98: 1607-1612, 2001.

4. Zhu WZ, Wang SQ, Chakir K, Kolbilka BK, Cheng H, Xiao RP*, Linkage of 1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/Calmodulin Kinase II, JOURNAL OF CLINICAL INVESTIGATION,111:617-625, 2003.

5. Xiao RP*, Cheng H, Lederer WJ, Suzuki T, Lakatta EG, Dual regulation of Ca2+/calmodulin-dependent Kinase II activity by membrane voltage and by calcium influx. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 91: 9659-9663, 1994.




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