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Cheng Li


Cheng Li


Email: lch3000(at)gmail(dot)com;


Lab Homepage: www.ChengLiLab.org


Research Area:

1. 生物信息学和计算生物学;
2. 癌症基因组学和个体化医疗;
3. 高通量生物数据分析中的统计建模。


Selected Publications:

1. Samur MK, Yan Z, Wang X, Cao Q, Munshi NC, Li C*, Shah PK*. canEvolve: A web portal for integrative oncogenomics. PLoS One. 2013;8(2):e56228. 
2. Parkin B, Ouillette P, Li Y, Keller J, Lam C, Roulston D, Li C, Shedden K, Malek SN. Clonal evolution and devolution following chemotherapy in adult acute myelogenous leukemia. Blood. 2013. 121(2):369-77. 
3. Yan Z, Shah PK, Amin SB, Samur MK, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C*. Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers. Nucleic Acids Res. 2012. 40(17):e135.
4. Huang N, Shah PK*, Li C*. Lessons from a decade of integrating cancer copy number alterations with gene expression profiles. Briefings in Bioinformatics. 2012; 13(3):305-16. 
5. Cao Q, Zhou M, Wang X, Meyer CA, Zhang Y, Chen Z, Li C*, Liu XS*. CaSNP: a database for interrogating copy number alterations of cancer genome from SNP array data. Nucleic Acids Res. 2011. 39(Database issue):D968-74. 
6. Chen M, Wang K, Zhang L, Li C*, Yang Y*. The discovery of putative urine markers for the specific detection of prostate tumor by integrative mining of public genomic profiles. PLoS One. 2011;6(12):e28552. 
7. Li C, Kim SW, Rai D, Bolla AR, Adhvaryu S, Kinney MC, Robetorye RS, Aguiar RC. Copy number abnormalities, MYC activity and the genetic fingerprint of normal B-cells mechanistically define the microRNA profile of DLBCL. Blood. 2009. 113(26):6681-90. 
8. Avet-Loiseau H, Li C, Magrangeas F, Gouraud W, Charbonnel C, Harousseau JL, Attal M, Marit G, Mathiot C, Facon T, Moreau P, Anderson KC, Campion L, Munshi NC, Minvielle S. Prognostic Significance of Copy-Number Alterations in Multiple Myeloma. J Clin Oncol. 2009. 27(27):4585-90.
9. Li C*, Beroukhim R, Weir BA, Winckler W, Garraway LA, Sellers WR, Meyerson M. Major copy proportion analysis of tumor samples using SNP arrays. BMC Bioinformatics. 2008; 9:204.
10. Li C. Automating dChip: toward reproducible sharing of microarray data analysis. BMC Bioinformatics. 2008; 9:231.
11. Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. PloS One. 2008; 3(10):e3329. 
12. Johnson WE, Li C*, Rabinovic A. Adjusting batch effects in microarray expression data using Empirical Bayes methods. Biostatistics. 2007; 8(1): 118-127. 
(* : Correspondence).



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