Web Map For Collection 中文 English
Home About us Organization Principal Investigators Research Education& Training Academic activities Facilities Careers Downloads Contact us
Location:Home - Principal Investigators
Yanyi Huang


Yanyi Huang


Email:   yanyi(at)pku(dot)edu(dot)cn

Office: Room 307, Integrated Science Research Center, Peking University, 100871


Research Area:

Huang group is working on technology development for integrative biology researches. Our current research interests include genome sequencing technologies, microfluidics, and bioimaging. We are developing a few key advanced technologies to facilitate genome sequencing and its applications, especially the novel chemistry and instruments for DNA sequencing, single-cell genome and transcriptome analysis, as well as epigenomic studies of limited number of cells. We also apply large-scale integrated microfluidic devices to perform quantitative biological studies. We are developing new imaging technologies and image processing algorithms to study the dynamics of cells and organisms.


Selected Publications:

1. Yongfan Men, Yusi Fu, Zitian Chen, Peter A. Sims, William J. Greenleaf, Yanyi Huang.* Digital polymerase chain reaction in an array of femtoliter PDMS microreactors. Analytical Chemistry 2012, 84(10), 4262-4266. 

2. Aaron M. Streets,# Xiannian Zhang,# Chen Cao,Yuhong Pang, Xinglong Wu, Liang Xiong, Lu Yang,Yusi Fu, Liang Zhao,* Fuchou Tang,* Yanyi Huang.* Microfluidic single-cell whole transcriptome sequencing. PNAS 2014, 111(19), 7048-7053. 

3. Jie Shen,# Dongqing Jiang,# Yusi Fu,# Xinglong Wu,# Hongshan Guo, Binxiao Feng, Yuhong Pang, Aaron M. Streets, Fuchou Tang,* Yanyi Huang.* H3K4me3 epigenomic landscape derived from ChIP-Seq of 1,000 mouse early embryonic cells. Cell Research 2015, 25(1), 143-147. 

4. Senlian Hong,# Tao Chen,# Yuntao Zhu, Ang Li, Yanyi Huang,* Xing Chen.* Live-cell stimulated Raman scattering imaging of alkyne-tagged biomolecules. Angewandte Chemie Int. Ed. 2014, 53(23), 5827-5831. 

5. Aaron M. Streets, Ang Li, Tao Chen, Yanyi Huang.* Imaging without fluorescence: Nonlinear optical microscopy for quantitative cellular imaging. Analytical Chemistry 2014, 86(17), 8506-8513. 

All right reserved Center For Life Sciences