Jie Qiao
Email: jie.qiao(at)pku(dot)edu(dot)cn；
Office: Peking University Third Hospital, 100191
Research Area:
Research field: Prevention and Treatment of Reproductive Endocrine Diseases, Epidemiology and Pathogenesis of Polycystic Ovary Syndrome, Mechanism Study of Gametogenesis and Early Embryo Development, Preimplantation Genetic Diagnosis, Safety Evaluation of assisted Reproductive Technology and Development of New Methods.
Selected Publications:
1.H.S.,Guo,P,Zhu,L.Y.,Yan,R.,Li,B.Q.,Hu,Y.,Lian,J.,Yan,X.L.,Ren,S.L.,Lin,J.S., Li,X.H.,Jin,X.D.,Shi,P.,Liu,X.Y.,Wang,W.,Wang,Y.,Wei,X.L.,Li,F.,Guo,X.L.,Wu,X.Y.,Fan,J.,Yong,L.,Wen,Sunney X.,Xie,F.C.,Tang*,J.,Qiao*. The DNA methylation landscape of human early embryos. Nature（2014）511, 606–610.
2.Jie Qiao*, Rong Li，Fertility preservation: challenges and opportunities, Lancet. 2014 Oct 4;384(9950):1246-7.
3.Hou, Y., Fan, W. Yan, L., Li, R., Lian, Y., Huang, J., Li, J., Xu, L., Tang, F.*, Xie, X.S*. and Qiao, J*. Genome analyses of single human oocytes. Cell(2013), 155,1492-506.
4.Zhang Y, Chen Q, Zhang H, Wang Q, Li R, Jin Y, Wang H, Ma T, Qiao J*, Duan E*. Aquaporin-dependent excessive intrauterine fluid accumulation is a major contributor in hyper-estrogen induced aberrant embryo implantation，Cell Res. 2015 Jan;25(1):139-42.
5.Yan, L., Yang, M., Guo, H., Yang, L., Wu ,J., Li, R., Li, P., Lian, Y., Zheng, X., Yan, J., Huang, J., Li, M., Wu, X., Wen, L., Lao, K.,R.Q., LI*, Qiao, J*. and Tang F*. Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Mol Biol(2013), 20, 1131-9.
6.Wen L, Li X, Yan L, Tan Y, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C*, Li R*, Tang F*, Qiao J*.Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.Genome Biol(2014) Mar 4;15(3):R49.
7.Qiao, J., Wang, Z.B., Feng, H.L., Miao, Y.L., Wang, Q., Yu, Y., Wei, Y.C., Yan, J., Wang, W.H., Shen, W., Sun, S.C., Schatten, H. and Sun, Q.Y*. The root of reduced fertility in aged women and possible therapentic options: Current status and future perspects. Mol Aspects Med(2014)38,54–85.
8.Qiao, J. and Feng, H.L. Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence. Hum Reprod Update (2011)17, 17-33.
9.Zhao, Y., Fu, L., Li, R., Wang, L.N., Yang, Y., Liu, N.N., Zhang, C.M., Wang, Y., Liu, P., Tu, B.B., Zhang, X. and Qiao, J*. Metabolic profiles characterizing different phenotypes of polycystic ovary syndrome: plasma metabolomics analysis. BMC Med(2012)10,153.
10.Zhao Y, Zhang C, Huang Y, Yu Y, Li R, Li M, Liu N, Liu P, Qiao J*. Up-Regulated Expression of WNT5a Increases Inflammation and Oxidative Stress via PI3K/AKT/NF-kappaB Signaling in the Granulosa Cells of PCOS Patients. J Clin Endocrinol Metab. 2015 Jan;100(1):201-11.