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Shiming Tang



Shiming Tang




Research Areas


We've established the first applicable system for long-term two-photon imaging in awake monkey, which has been successfully applied in both primary/advanced visual cortex and prefrontal cortex, and enabled neuronal population imaging at single-cell resolution and dendritic imaging at single-spine resolution. Combining with electrophysiology and optogenetics manipulation, we investigate the neural mechanism of visual cognition, including object and face recognition, selective attention, working memory, etc.


Selected Publications

1. Ju N, Jiang R, Macknik S, Martinez-Conde5 S, Tang S*. (2018). Long-term all-optical interrogation of cortical neurons in awake-behaving nonhuman primates. PLOS Boilogy, 16(8): e2005839.
2. Zhang Y*, Lee TS, Li M, Liu F, Tang S*. (2018). Convolutional neural network models of V1 responses to complex patterns. Journal of Computational Neuroscience. 2018 (2): 1-22.
3. Tang S*, Zhang Y, Li Z, Li M, Liu F, Jian H, Lee TS*. (2018). Large-scale two-photon imaging revealed super-sparse population codes in V1 superficial layer of awake monkeys. eLife 7: e33370 doi: 10.7554/eLife.33370.
4. Tang S*, Lee TS, Li M, Zhang Y, Xu Y, Liu F, Teo B, Jian H. (2018). Complex Pattern Selectivity in Macaque Primary Visual Cortex Revealed by Large-Scale Two-Photon Imaging. Current Biology 28, 38–48.
5. Li M, Liu F, Jiang H, Lee TS, Tang S*. (2017). Long-Term Two-Photon Imaging in Awake Macaque Monkey. Neuron 93, 1049–1057.
6. Li M, Liu F, Juusola, M, Tang S*. (2014). Perceptual Color Map in Macaque Visual Area V4. The Journal of Neuroscience, 34 (1), 202-217.
7. Tang S*, Wolf R, Xu SP, Heisenberg M*. (2004). Visual pattern recognition in Drosophila is invariant for retinal position. Science, 305, 1020-1022.
8. Tang S*, Guo A*. (2001). Choice behavior of Drosophila facing contradictory visual cues. Science, 294, 1543-1547.


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