Articles
Li JZ, Ye J, Xue BF, Qi JZ, Zhang J, Zhou ZH, Li Q, Wen ZL, Li P. Cideb deficient mice have improved insulin sensitivity and are resistant to high fat diet-induced obesity and liver steatosis. DIABETES 56: 2523-2532, 2007
Time:2011-11-17Author:李蓬KeyWord:
Abstract OBJECTIVE: Our previous study suggests that Cidea, a member of Cide family proteins that share sequence homology with the DNA fragmentation factor and are expressed at high levels in brown adipose tissue, plays an important role in the development of obesity. Cideb, another member of Cide family protein, is highly expressed in the liver. We would like to understand the physiological role of Cideb in the regulation of energy expenditure and lipid metabolism. |
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