王伟
邮箱：oneway1985@pku.edu.cn
研究领域：植物抗逆的时空调控、无膜细胞器、植物生物钟
研究兴趣：
本实验室聚焦植物抗逆的时空调控机制——这是气候波动下保障作物稳产与农业韧性的核心命题。我们以两个交叉视角切入：一是空间侧，动态无膜细胞器（生物分子凝聚体）通过相分离驱动的快速亚细胞重排，实现胁迫信号的局域放大与高效响应；二是时间侧，生物钟系统为全株建立节律性时序框架，使不同胁迫应答模式在"何时启动、投入多少"上达成最优权衡。
代表性科研论文 :
1.Wang, S. et al. Discovery and heterologous reconstitution of a plant noncanonical quasi-circadian gene regulatory network. Cell (2026). https://doi.org/https://doi.org/10.1016/j.cell.2026.04.033
2 Wang, X. et al. Hijacking the host clock: a nematode effector antagonizes soybean circadian defense and translation control. Adv Sci (Weinh), e18591 (2026). https://doi.org/10.1002/advs.202518591
3 Zhao, S. et al. Duet between stress granules and glutathionylation regulates cytosolic redox state to maintain proteostasis in Arabidopsis. Molecular Plant 19, 606-628 (2026). https://doi.org/https://doi.org/10.1016/j.molp.2025.12.018
4 Xie, Z. et al. Proteasome resides in and dismantles plant heat stress granules constitutively. Molecular Cell 84, 3320-3335.e3327 (2024). https://doi.org/10.1016/j.molcel.2024.07.033
5 Xie, Z. et al. Phenolic acid-induced phase separation and translation inhibition mediate plant interspecific competition. Nature Plants 9, 1481-1499 (2023). https://doi.org/10.1038/s41477-023-01499-6
6 Chen, C. et al. Aptamer-based nanointerferometer enables amplification-free ultrasensitive detection and differentiation of SARS-CoV-2 variants. Analytica Chimica Acta 1260, 341207 (2023). https://doi.org/https://doi.org/10.1016/j.aca.2023.341207
7 Li, M. et al. Comprehensive mapping of abiotic stress inputs into the soybean circadian clock. Proceedings of the National Academy of Sciences of the United States of America 116, 23840-23849 (2019). https://doi.org/10.1073/pnas.1708508116
8 Chen, C. et al. Development of a structure-switching aptamer-based nanosensor for salicylic acid detection. Biosensors and Bioelectronics 140, 111342 (2019). https://doi.org/https://doi.org/10.1016/j.bios.2019.111342
9 Zhou, M. et al. Redox rhythm reinforces the circadian clock to gate immune response. Nature 523, 472-476 (2015). https://doi.org/10.1038/nature14449
10 Wang, W. et al. Timing of plant immune responses by a central circadian regulator. Nature 470, 110-114 (2011). https://doi.org/10.1038/nature09766
