Seminar

Topic: CHO cells: Workhorse for ton-quantity production of recombinant protein pharmaceuticals - the why, the how and what now

Speaker: Prof. Florian M. Wurm,

Cellular Biotechnology Laboratory,

Interfaculty Institute of Bioengineering ,

Lausanne Federal Polytechnic University, Switzerland – CH.

Abstract:

Today’s high yielding manufacturing processes for protein pharmaceuticals have made Chinese Hamster Ovary cells the most important host system for pharma-production. Ton quantities of antibodies and other products generate values in excess of 50 billion dollar annually. This talk will cover almost 30 years of history of these unique cells and will explain how the entire global industry has followed to use these immortalized cell lines with a rather undefined genotype and unique genetic and physiological issues for the generation of the most valuable products needed today.

The talk will also highlight further opportunities for societies that have only lately entered this field, based on the tremendous knowledge that has been accumulated, to generate both new and “old” (biosimilar) products but doing so at lower cost and faster than ever before.

Host: Prof. Yigong Shi

Date: 2:00PM-3:00PM, Aug. 28 (Wednesday)

Venue: B323, Medical School Building

Welcome!