JIZONG WANG
E-mail: wangjizong@tsinghua.edu.cn
Discipline direction: Plant Science and Structural Biology
Research area:
Light serves as both the primary energy source for photosynthesis and a critical environmental signal that regulates the entire plant life cycle. My laboratory focuses on the cutting-edge fields of light perception, signal transduction, and energy utilization in plants. By integrating multidisciplinary approaches, including biochemistry, structural biology, and genetics, we are dedicated to two key research areas:
1.Red/far-red light signal transduction in plants;
2.Biosynthesis of photosynthetic pigments.
Selected publications:
1.Chi C#, Wang ZD#, Wang RH, Wang JZ*. (2025). Production of plant phytochromes by combining insect cells and bacterial expression systems. Methods Mol. Biol. 2970:69-80.
2.Wang ZD#, Wang WF#, Zhao DD#, Song YP#, Lin XL#, Shen M, Chi C, Xu B, Zhao J, Deng XW*, Wang JZ*. (2024). Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor. Cell 187:6235-6250.
3.Zhang YX#, Lin XL#, Ma CY#, Zhao J#, Shang XJ, Wang ZD, Xu B, Gao N, Deng XW*, Wang JZ*. (2023). Structural insights into plant phytochromes A as a highly sensitized photoreceptor. Cell Res. 33:806-809.
4.Wang JZ*, Song W*, Chai JJ*. (2022). Structure, biochemical function, and signaling mechanism of plant NLRs. Mol. Plant 16:75-95.
5.Wang JZ#, Hu MJ#, Wang J#, Qi JF, Han ZF, Wang GX, Qi YJ, Wang HW*, Zhou JM*, Chai JJ*. (2019). Reconstitution and structure of a plant NLR resistosome conferring immunity. Science 364:eaav5870.
6.Wang JZ#, Wang J#, Hu MJ#, Wu S, Qi JF, Wang GX, Han ZF, Qi YJ, Gao N, Wang HW*, Zhou JM*, Chai JJ*. (2019). Ligand-triggered allosteric ADP release primes a plant NLR complex. Science 364:eaav5868.
7.Wang JZ#, Li HJ#, Han ZF, Zhang HQ, Wang T, Lin GZ, Chang JB, Yang WC*, Chai JJ*. (2015). Allosteric receptor activation by the plant peptide hormone phytosulfokine. Nature 525:265-268.
#: Co-first author; *: Corresponding author
