Mapping the landscape of intercellular crosstalk in health and metabolic disease
Jiandie Lin PhD
Life Sciences Institute
Department of Cell & Developmental Biology
University of Michigan
Ann Arbor, MI 48109-2216, USA
Biography:After completing his undergraduate work at Peking Univeristy, Professor Jiandie Lin received his Ph.D. in Biochemistry and Molecular Biology and Cell Biology at Northwestern University in Evanston, IL. He did his postdoctoral training with Dr. Bruce Spiegelman at Dana-Farber Cancer Institute and Harvard Medical School in Boston, MA. In 2005, he started his independent research in the Life Sciences Institute at the University of Michigan. Dr. Lin currently holds Bradley M. Patten Collegiate Professor of Life Sciences and Professor of Cell & Developmental Biology. Dr. Lin’s research focuses on investigating the mechanisms of metabolic programming in tissue development, homeostasis and disease, and mapping the landscape of metabolic secretome and crosstalk.
Abstract:Intercellular crosstalk via secreted ligands and membrane receptors is fundamental to organ biology, metabolism and disease. Our studies focus on delineating the biological roles and mechanisms of novel endocrine factors released by adipose tissue and the liver. We seek to establish a framework of tissue secretome at the single-cell level and map the landscape of cell-cell crosstalk in metabolic tissues.
Time: Oct. 22nd, 2018, 16:30-17:30
Venue: New Biology Building, Room B143
Host: Dr. Ligong Chen
举办单位:生命科学联合中心